Literature summary for 1.13.11.52 extracted from

Manandhar, S.P.; Shimada, H.; Nagano, S.; Egawa, T.; Ishimura, Y.
Subunit structure of recombinant rat liver L-tryptophan 2,3-dioxygenase (2002), Int. Congr. Ser., 1233, 161-169.

No PubMed abstract available

Search for more literature for 1.13.11.52

Cloned(Commentary)

Cloned (Comment)	Organism
enzyme with a His tag at the N-terminus is expressed in Escherichia coli JM109 harboring plasmid pUC18 carrying the full-length cDNA of TDO	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Subunits

Subunits	Comment	Organism
?	a 46000 Da species and a 49000 Da species are detected by SDS-PAGE. The 46000 Da species is shorter than the 49000 Da species by 19 amino acid residues including six His residues at the end. A limited proteolysis appears to occur between Tyr13 and Thr14 of the original polypeptide chain	Rattus norvegicus

Synonyms

Synonyms	Comment	Organism
L-tryptophan 2,3-dioxygenase	-	Rattus norvegicus
TDO	-	Rattus norvegicus

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
additional information	-	additional information	-	Rattus norvegicus

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Release 2023.1 (January 2023)