Protein Variants | Comment | Organism |
---|---|---|
R183Q | mutant does not bind OH- under conditions where the wild-type enzyme is completely converted to the heme hydroxide. Mutant does not bind F- | Dechloromonas aromatica |
W227F | mutant does not bind OH- under conditions where the wild-type enzyme is completely converted to the heme hydroxide. Mutant does not bind F- | Dechloromonas aromatica |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chloride | upon cooperative binding of Cl-, Cld remains pentacoordinate and high-spin | Dechloromonas aromatica | |
chloride | cooperative binding of Cl- to Cld drives formation of a hexacoordinate, high-spin aqua heme | Klebsiella pneumoniae | |
fluoride | fluoride coordinates to the heme iron in Cld exhibiting ny(FeIII-F) band at 390 per cm. Strong H-bond donation happens to the F- ligand | Dechloromonas aromatica | |
fluoride | fluoride coordinates to the heme iron in Cld exhibiting ny(FeIII-F) band at 385 per cm. Strong H-bond donation happens to the F- ligand | Klebsiella pneumoniae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | vibrational frequency correlations between either ny(FeIII-F) or ny(FeIII-OH) and ny(FeII-His) orthogonalize proximal and distal effects on the bonding between iron and exogenous pi-donor ligands | Klebsiella pneumoniae | |
Iron | vibrational frequency correlations between either ny(FeIII-F) or ny(FeIII-OH) and ny(FeII-His) orthogonalize proximal and distal effects on the bonding between iron and exogenous pi-donor ligands | Dechloromonas aromatica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dechloromonas aromatica | Q47CX0 | - |
- |
Dechloromonas aromatica RCB | Q47CX0 | - |
- |
Klebsiella pneumoniae | - |
- |
- |
Klebsiella pneumoniae MGH 78578 | - |
- |
- |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Dechloromonas aromatica |