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Literature summary for 1.13.11.45 extracted from

  • Hoffmann, I.; Hamberg, M.; Lindh, R.; Oliw, E.H.
    Novel insights into cyclooxygenases, linoleate diol synthases, and lipoxygenases from deuterium kinetic isotope effects and oxidation of substrate analogs (2012), Biochim. Biophys. Acta, 1821, 1508-1517.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ non-heme iron Glycine max

Organism

Organism UniProt Comment Textmining
Glycine max
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(9E,12Z)-octadeca-9,12-dienoic acid + O2 sLOX-1 oxidizes (9E,12Z)18:2 to 9-hydroperoxyoctadecadienoic acid in an R/S ratio of 60/40 and to 13-hydroperoxyoctadecadienoic acid Glycine max ?
-
?
(9Z,12E)-octadeca-9,12-dienoic acid + O2 sLOX-1 oxidizes (9Z,12E)18:2 slowly to the 9-hydroperoxy metabolite with 10E,12E configuration as the main product (65%) and to 13-hydroperoxyoctadecadienoic acid Glycine max ?
-
?
additional information (9Z,12E)18:2 is not oxidized at a detectable rate. sLOX-1 oxidizes (9E,12Z)18:2 more efficiently than (9Z,12E)18:2 Glycine max ?
-
?

Synonyms

Synonyms Comment Organism
LOX-1
-
Glycine max

Temperature Optimum [┬░C]

Temperature Optimum [┬░C] Temperature Optimum Maximum [┬░C] Comment Organism
23
-
assay at Glycine max

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
assay at Glycine max