Inhibitors | Comment | Organism | Structure |
---|---|---|---|
MK886 | specific inhibitor of 5-hydroperoxyeicosatetraenoic acid synthesis by the enzyme | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-hydroperoxyeicosatetraenoic acid | Homo sapiens | - |
leukotriene A4 + H2O | is unstable and metabolized to leukotriene B4 | ? | |
arachidonic acid + O2 | Homo sapiens | - |
5-hydroperoxyeicosatetraenoic acid | - |
? | |
additional information | Homo sapiens | the enzyme, catalyzing the key step in leukotriene biosynthesis, interacts with methyl jasmonate, which is probably involved in the anticarcinogenic activity of methyl jasmonate inducing apoptosis, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
DU-145 cell | - |
Homo sapiens | - |
PC-3 cell | - |
Homo sapiens | - |
prostate adenocarcinoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-hydroperoxyeicosatetraenoic acid | - |
Homo sapiens | leukotriene A4 + H2O | - |
? | |
5-hydroperoxyeicosatetraenoic acid | - |
Homo sapiens | leukotriene A4 + H2O | is unstable and metabolized to leukotriene B4 | ? | |
arachidonic acid + O2 | - |
Homo sapiens | 5-hydroperoxyeicosatetraenoic acid | - |
? | |
additional information | the enzyme, catalyzing the key step in leukotriene biosynthesis, interacts with methyl jasmonate, which is probably involved in the anticarcinogenic activity of methyl jasmonate inducing apoptosis, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
5-lipoxygenase | - |
Homo sapiens |
5-LOX | - |
Homo sapiens |