Inhibitors | Comment | Organism | Structure |
---|---|---|---|
miogadial | potent inhibitor, IC50: 0.004 mM | Homo sapiens | |
miogatrial | potent inhibitor, IC50: 0.0075 mM | Homo sapiens | |
additional information | no inhibition by galanal A, galanal B and 8beta(17)-epoxy-15-hydroxy-12(E)-labden-16-al | Homo sapiens | |
polygodial | strong inhibitory activity, IC50: 0.0086 mM | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + O2 | - |
Homo sapiens | (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
5-LOX | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.004 | - |
potent inhibitor, IC50: 0.004 mM | Homo sapiens | miogadial | |
0.0075 | - |
potent inhibitor, IC50: 0.0075 mM | Homo sapiens | miogatrial | |
0.0086 | - |
strong inhibitory activity, IC50: 0.0086 mM | Homo sapiens | polygodial |