Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ATP | stimulates | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
AA861 | - |
Sus scrofa | |
Cirsiliol | - |
Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
72000 | - |
x * 72000, SDS-PAGE | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leukocyte | - |
Sus scrofa | - |
Storage Stability | Organism |
---|---|
-70°C, 1 week, no appreciable inactivation | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(12S)hydroperoxy-5,8-cis-10-trans-13-cis-eicosatetraenoic acid + O2 | 22% of the activity with arachidonic acid | Sus scrofa | (5S,12S)-dihydroperoxy-5,8-cis-10-trans-13-cis-eicosatetraenoic acid | - |
? | |
(15S)-hydroperoxy-5,8,11-cis-13-trans-eicosatetraenoic acid + O2 | 30% of the activity with arachidonic acid | Sus scrofa | (5S,15S)-dihydroperoxy-5,8,11-cis-13-trans-eicosatetraenoic acid | - |
? | |
arachidonate + O2 | i.e. 5,8,11,14-eicosatetraenoic acid | Sus scrofa | (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate | + leukotriene A4 | ? |
Subunits | Comment | Organism |
---|---|---|
? | x * 72000, SDS-PAGE | Sus scrofa |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
2 | - |
half-life: 24 h | Sus scrofa |
24 | - |
1 h, 50% loss of activity | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8 | - |
Sus scrofa |