Literature summary for 1.13.11.33 extracted from

Lee, J.; Kim, T.H.; Oh, D.K.
Bioconversion of arachidonic acid into human 14,15-hepoxilin B3 and 13,14,15-trioxilin B3 by recombinant cells expressing microbial 15-lipoxygenase without and with epoxide hydrolase (2020), Biotechnol. Lett., 42, 2001-2009 .

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Application

Application	Comment	Organism
synthesis	production of 13-hydroxy-14,15-epoxy-eicosatrienoic acid (14,15-hepoxilin B3, 14,15-HXB3) and 13,14,15-trihydroxyeicosatrienoic acid (13,14,15-trioxilin B3, 13,14,15-TrXB3) from arachidonic acid in Escherichia coli expressing Archangium violaceum 15-LOX in presence and absence of Myxococcus xanthus epoxide hydrolase. Under the optimal conditions of 30 g cells/l, 200 mM ARA, 25°C, and initial pH 7.5, the cells convert 200 mM arachidonic acid into 192 mM 14,15-HXB3 and 100 mM 13,14,15-TrXB3 for 150 min, with conversion yields of 96% and 51%	Archangium violaceum

Organism

Organism	UniProt	Comment	Textmining
Archangium violaceum	-	-	-
Archangium violaceum DSM 52858	-	-	-

Synonyms

Synonyms	Comment	Organism
15-LOX	-	Archangium violaceum

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Release 2023.1 (January 2023)