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Literature summary for 1.13.11.33 extracted from
- Overexpression of human 15(S)-lipoxygenase-1 in RAW macrophages leads to increased cholesterol mobilization and reverse cholesterol transport (2009), Arterioscler. Thromb. Vasc. Biol., 29, 837-842.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| RAW 267.4 murine macrophages stably transfected to overexpress 15-LO-1 | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| arachidonate + O2 | - |
Homo sapiens | (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 15(S)-lipoxygenase-1 | - |
Homo sapiens |
| 15-LO-1 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | overexpression of human 15-LO-1 in RAW macrophages promotes reverse cholesterol transport through increased cholesteryl ester hydrolysis and ABCA1-mediated cholesterol efflux | Homo sapiens |
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