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Literature summary for 1.13.11.33 extracted from

  • Utenova, B.T.; Malterud, K.E.; Rise, F.
    Antioxidant activity of O-protected derivatives of (-)-epigallocatechin-3-gallate: inhibition of soybean and rabbit 15-lipoxygenases (2007), ARKIVOC, 2007, 6-16.
No PubMed abstract available
Search for more literature for 1.13.11.33

Inhibitors

Inhibitors Comment Organism Structure
(-)-5,7-O-diacetyl-3',4',5'-O-triacetylepigallocatechin-3-O-(3'',4'',5''-O-triacetyl)gallate IC50: 0.061 mM Oryctolagus cuniculus
(-)-5,7-O-dibutyryl-3',4',5'-O-tributyrylepigallocatechin-3-O-(3'',4'',5''-O-tributyryl) gallate IC50: 0.033 mM Oryctolagus cuniculus
(-)-5,7-O-dimethyl-3',4',5'-O-trimethylepigallocatechin-3-O-(3'',4'',5''-O-trimethyl) gallate IC50: 0.03 mM Oryctolagus cuniculus
(-)-5,7-O-dipropionyl-3',4',5'-O-tripropionylepigallocatechin-3-O-(3'',4'',5''-O-tripropionyl) gallate IC50: 0.031 mM Oryctolagus cuniculus
(-)-epigallocatechin-3-gallate IC50: 0.1 mM Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
reticulocyte
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + O2
-
 Oryctolagus cuniculus (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyeicosa-5,8,11,13-tetraenoate
-
 ?

Synonyms

Synonyms Comment Organism
15-lipoxygenase
-
 Oryctolagus cuniculus
15-LO
-
 Oryctolagus cuniculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.03
-
 IC50: 0.03 mM Oryctolagus cuniculus (-)-5,7-O-dimethyl-3',4',5'-O-trimethylepigallocatechin-3-O-(3'',4'',5''-O-trimethyl) gallate
0.031
-
 IC50: 0.031 mM Oryctolagus cuniculus (-)-5,7-O-dipropionyl-3',4',5'-O-tripropionylepigallocatechin-3-O-(3'',4'',5''-O-tripropionyl) gallate
0.033
-
 IC50: 0.033 mM Oryctolagus cuniculus (-)-5,7-O-dibutyryl-3',4',5'-O-tributyrylepigallocatechin-3-O-(3'',4'',5''-O-tributyryl) gallate
0.061
-
 IC50: 0.061 mM Oryctolagus cuniculus (-)-5,7-O-diacetyl-3',4',5'-O-triacetylepigallocatechin-3-O-(3'',4'',5''-O-triacetyl)gallate
0.1
-
 IC50: 0.1 mM Oryctolagus cuniculus (-)-epigallocatechin-3-gallate