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Literature summary for 1.13.11.33 extracted from

  • Sigal, E.; Grunberger, D.; Cashman, J.R.; Craik, C.S.; Caughey, G.H.; Nadel, J.A.
    Arachidonate 15-lipoxygenase from human eosinophil-enriched leukocytes: partial purification and properties (1988), Biochem. Biophys. Res. Commun., 150, 376-383.
    View publication on PubMed
Search for more literature for 1.13.11.33

Activating Compound

Activating Compound Comment Organism Structure
phosphatidylcholine stimulates Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
ATP
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.068
-
 arachidonic acid
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
eosinophil 15-lipoxygenase activity is 100fold greater in eosinophils than in neutrophils Homo sapiens
-
leukocyte eosinophil-enriched leukocytes Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.125
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + O2
-
 Homo sapiens (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyeicosa-5,8,11,13-tetraenoate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 8.5
-
 Homo sapiens