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Literature summary for 1.13.11.27 extracted from

  • Abbott, M.T.; Udenfriend, S.
    alpha-Ketoglutarate-coupled dioxygenases (1974), Mol. Mech. Oxygen Activ. (Hayaishi, O., ed.) Academic Press, New York, , 167-214.
No PubMed abstract available
Search for more literature for 1.13.11.27

Activating Compound

Activating Compound Comment Organism Structure
Trypsin liver enzyme appears to be present in an inactive form which can be activated by treatment with trypsin or by autolysis Frog

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.04
-
 4-hydroxyphenylpyruvate
-
 Sus scrofa
0.04
-
 4-hydroxyphenylpyruvate
-
 Canis lupus familiaris
0.5
-
 4-hydroxyphenylpyruvate
-
 Frog

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
85000
-
 gel filtration Sus scrofa

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Canis lupus familiaris
-
-
-
Cavia porcellus
-
-
-
Didelphidae
-
-
-
Frog
-
-
-
Gallus gallus
-
-
-
Homo sapiens
-
-
-
Oncorhynchus mykiss
-
-
-
Oryctolagus cuniculus
-
-
-
Platyrrhini
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-
kidney
-
 Rattus norvegicus
-
kidney
-
 Platyrrhini
-
liver
-
 Gallus gallus
-
liver
-
 Homo sapiens
-
liver
-
 Rattus norvegicus
-
liver
-
 Sus scrofa
-
liver
-
 Bos taurus
-
liver
-
 Canis lupus familiaris
-
liver
-
 Oncorhynchus mykiss
-
liver
-
 Didelphidae
-
additional information no enzymatic activity in any tissue other than liver and kidney Gallus gallus
-
additional information no enzymatic activity in any tissue other than liver and kidney Cavia porcellus
-
additional information no enzymatic activity in any tissue other than liver and kidney Homo sapiens
-
additional information no enzymatic activity in any tissue other than liver and kidney Rattus norvegicus
-
additional information no enzymatic activity in any tissue other than liver and kidney Sus scrofa
-
additional information no enzymatic activity in any tissue other than liver and kidney Bos taurus
-
additional information no enzymatic activity in any tissue other than liver and kidney Oryctolagus cuniculus
-
additional information no enzymatic activity in any tissue other than liver and kidney Canis lupus familiaris
-
additional information no enzymatic activity in any tissue other than liver and kidney Frog
-
additional information no enzymatic activity in any tissue other than liver and kidney Platyrrhini
-
additional information no enzymatic activity in any tissue other than liver and kidney Oncorhynchus mykiss
-
additional information no enzymatic activity in any tissue other than liver and kidney Didelphidae
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-hydroxyphenylpyruvate + O2
-
 Gallus gallus homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Cavia porcellus homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Homo sapiens homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Rattus norvegicus homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Sus scrofa homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Bos taurus homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Oryctolagus cuniculus homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Canis lupus familiaris homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Frog homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Platyrrhini homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Oncorhynchus mykiss homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Didelphidae homogentisate + CO2
-
 ?