The genes encoding the hydroxylase of 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione in steroid degradation in Comamonas testosteroni TA441

Horinouchi, M.; Hayashi, T.; Kudo, T.; J. Steroid Biochem. Mol. Biol. 92, 143-154 (2004)

Data extracted from this reference:

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2

Comamonas testosteroni

-

3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate

-

-

?

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

Substrate Product ID

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2

-

659813

Comamonas testosteroni

3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate

-

-

-

?

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2

Comamonas testosteroni

-

3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate

-

-

?

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

ID

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2

-

659813

Comamonas testosteroni

3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate

-

-

-

?

No.

1st author

Pub Med

title

organims

journal

volume

pages

year

Activating Compound

Application

Cloned(Commentary)

Crystallization (Commentary)

Engineering

General Stability

Inhibitors

KM Value [mM]

Localization

Metals/Ions

Molecular Weight [Da]

Natural Substrates/ Products (Substrates)

Organic Solvent Stability

Organism

Oxidation Stability

Posttranslational Modification

Purification (Commentary)

Reaction

Renatured (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Storage Stability

Substrates and Products (Substrate)

Subunits

Synonyms

Temperature Optimum [°C]

Temperature Range [°C]

Temperature Stability [°C]

Turnover Number [1/s]

pH Optimum

pH Range

pH Stability

Cofactor

Ki Value [mM]

pI Value

IC50 Value

Activating Compound (protein specific)

Application (protein specific)

Cloned(Commentary) (protein specific)

Cofactor (protein specific)

Crystallization (Commentary) (protein specific)

Engineering (protein specific)

General Stability (protein specific)

IC50 Value (protein specific)

Inhibitors (protein specific)

Ki Value [mM] (protein specific)

KM Value [mM] (protein specific)

Localization (protein specific)

Metals/Ions (protein specific)

Molecular Weight [Da] (protein specific)

Natural Substrates/ Products (Substrates) (protein specific)

Organic Solvent Stability (protein specific)

Oxidation Stability (protein specific)

Posttranslational Modification (protein specific)

Purification (Commentary) (protein specific)

Renatured (Commentary) (protein specific)

Source Tissue (protein specific)

Specific Activity [micromol/min/mg] (protein specific)

Storage Stability (protein specific)

Substrates and Products (Substrate) (protein specific)

Subunits (protein specific)

Temperature Optimum [°C] (protein specific)

Temperature Range [°C] (protein specific)

Temperature Stability [°C] (protein specific)

Turnover Number [1/s] (protein specific)

pH Optimum (protein specific)

pH Range (protein specific)

pH Stability (protein specific)

pI Value (protein specific)

Expression

General Information

General Information (protein specific)

Expression (protein specific)

KCat/KM [mM/s]

KCat/KM [mM/s] (protein specific)

659813

Horinouchi

The genes encoding the hydroxy ...

Comamonas testosteroni

J. Steroid Biochem. Mol. Biol.

92

143-154

2004

-

-

-

-

-

-

-

-

-

-

-

1

-

1

-

-

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-

-

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-

-

1

-

1

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-

-

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-

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-

-

-

-

-

-

-

-

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1

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-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

396333

Nozaki

-

Nonheme iron dioxygenase ...

Rhodococcus hoagii

Mol. Mech. Oxygen Activ. (Hayaishi, O., ed.) Academic Press, New York

135-165

1974

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-

-

-

-

1

6

-

-

1

1

1

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1

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1

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3

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1

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6

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1

1

1

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3

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-

439527

Tai

3,4-Dihydroxy-9,10-secoandrost ...

Rhodococcus hoagii

J. Biol. Chem.

245

5062-5071

1970

-

-

-

-

-

-

3

-

-

1

2

1

-

3

-

-

1

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1

1

3

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-

1

1

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3

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-

-

1

2

1

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1

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1

1

3

-

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-

1

1

-

-

-

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-

-

-

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439528

Gibson

Mechanisms of steroid oxidatio ...

Rhodococcus hoagii

J. Biol. Chem.

241

551-559

1966

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1

1

1

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1

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1

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