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Literature summary for 1.13.11.20 extracted from

  • Lombardini, J.B.; Singer, T.P.; Boyer, P.D.
    Cystein oxygenase. II. Studies on the mechanism of the reaction with 18oxygen (1969), J. Biol. Chem., 244, 1172-1175.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
NAD(P)H required for fully activity Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Fe Fe2+ required for fully activity Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
L-cysteine + O2 = 3-sulfinoalanine mechanism Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-cysteine + O2
-
Rattus norvegicus 3-sulfino-L-alanine
-
?

Cofactor

Cofactor Comment Organism Structure
additional information unidentified heat-stable cofactor Rattus norvegicus
additional information NADPH or NADH do not act as cosubstrates, most of added NADPH disappears from the incubation mixture during the first 10 min, while cysteinesulfinic acid remains linear for up to 30 min, the role of NADHP or NADH may be one of stabilization, as allosteric activators or other type of activating agents Rattus norvegicus