Literature summary for 1.12.99.6 extracted from

Tye, J.W.; Darensbourg, M.Y.; Hall, M.B.
Refining the active site structure of iron-iron hydrogenase using computational infrared spectroscopy (2008), Inorg. Chem., 47, 2380-2388.

Search for more literature for 1.12.99.6

Inhibitors

Inhibitors	Comment	Organism	Structure
CO	binds terminally to the distal iron center	Desulfovibrio vulgaris
CO	binds terminally to the distal iron center	Desulfovibrio vulgaris str. Hildenborough

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Fe	the Hred form is assigned as a mixture of an Fe(I)Fe(I) form with an open site on the distal iron center and either a Fe(I)Fe(I) form in which the distal cyanide is protonated or a Fe(II)Fe(II) form with a bridging hydride ligand. The Hox form is assigned as a valence-localized Fe(I)Fe(II) redox level with an open site at the distal iron. The Hox air form is assigned as an Fe(II)Fe(II) redox level with OH- or OOH- bound to the distal iron center that may or may not have an oxygen atom bound to one of the sulfur atoms of the dithiolate linker	Desulfovibrio vulgaris
Fe	the Hred form is assigned as a mixture of an Fe(I)Fe(I) form with an open site on the distal iron center and either a Fe(I)Fe(I) form in which the distal cyanide is protonated or a Fe(II)Fe(II) form with a bridging hydride ligand. The Hox form is assigned as a valence-localized Fe(I)Fe(II) redox level with an open site at the distal iron. The Hox air form is assigned as an Fe(II)Fe(II) redox level with OH- or OOH- bound to the distal iron center that may or may not have an oxygen atom bound to one of the sulfur atoms of the dithiolate linker	Desulfovibrio vulgaris str. Hildenborough

Organism

Organism	UniProt	Comment	Textmining
Desulfovibrio vulgaris	-	-	-
Desulfovibrio vulgaris str. Hildenborough	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
H2 + oxidized electron acceptor	-	Desulfovibrio vulgaris	H+ + reduced electron acceptor	-	?
H2 + oxidized electron acceptor	-	Desulfovibrio vulgaris str. Hildenborough	H+ + reduced electron acceptor	-	?

Synonyms

Synonyms	Comment	Organism
[FeFe]H2ase	-	Desulfovibrio vulgaris
[FeFe]H2ase	-	Desulfovibrio vulgaris str. Hildenborough

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Release 2023.1 (January 2023)