Literature summary for 1.12.98.4 extracted from

Silva, P.; De Castro, B.; Hagen, W.
On the prosthetic groups of the NiFe sulfhydrogenase from Pyrococcus furiosus Topology, structure, and temperature-dependent redox chemistry (1999), J. Biol. Inorg. Chem., 4, 284-291 .

Search for more literature for 1.12.98.4

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Iron	the alpha-subunit carries the NiFe dinuclear center	Pyrococcus furiosus
Nickel	the alpha-subunit carries the NiFe dinuclear center	Pyrococcus furiosus

Organism

Organism	UniProt	Comment	Textmining
Pyrococcus furiosus	E7FI44 AND Q8U2E5 AND Q8U2E4 AND E7FHU4	E7FI44: alpha-subunit, Q8U2E5: beta-subunit, Q8U2E4: gamma-subunit, E7FHU4: delta-subunit	-

Purification (Commentary)

Purification (Comment)	Organism
-	Pyrococcus furiosus

Subunits

Subunits	Comment	Organism
heterotetramer	alphabetagammadelta hetreotetramer, 1 * 48700 + 1 * 41800 + 33200 + 29600	Pyrococcus furiosus

Synonyms

Synonyms	Comment	Organism
NiFe sulfhydrogenase	-	Pyrococcus furiosus

Cofactor

Cofactor	Comment	Organism	Structure
FAD	the gamma-subunit contains one FAD molecule	Pyrococcus furiosus
[2Fe-2S]-center	the gamma-subunit contains one 2Fe-2S cluster	Pyrococcus furiosus
[4Fe-4S]-center	the beta subunit contains at least two [4Fe-4S] cubanes. The delta-subunit contains three [4Fe-4S] cubanes	Pyrococcus furiosus
[Ni-Fe]-center	the alpha-subunit carries the NiFe dinuclear center	Pyrococcus furiosus

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Release 2023.1 (January 2023)