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Literature summary for 1.11.2.2 extracted from
- Inhibition of myeloperoxidase-mediated protein nitration by tempol: Kinetics, mechanism, and implications (2008), Proc. Natl. Acad. Sci. USA, 105, 8191-8196.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-hydroxy-2,2,6,6-tetra-methyl-1-piperidinyloxy radical | tempol, 0.01 mM tempol efficiently inhibits peroxidase-mediated RNase nitration | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leukocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | myeloperoxidase mediates protein tyrosine nitration | Homo sapiens | ? | - |
? | |
| NO2- + H2O2 | - |
Homo sapiens | ? | - |
? | |
| tyrosine + H2O2 | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MPO | - |
Homo sapiens |
| myeloperoxidase | - |
Homo sapiens |
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