Literature summary for 1.11.2.2 extracted from

Ghibaudi, E.; Laurenti, E.; Pacchiardo, C.; Suriano, G.; Moguilevsky, N.; Pia Ferrari, R.
Organic and inorganic substrates as probes for comparing native bovine lactoperoxidase and recombinant human myeloperoxidase (2003), J. Inorg. Biochem., 94, 146-154.

Search for more literature for 1.11.2.2

Cloned(Commentary)

Cloned (Comment)	Organism
expression in CHO cells	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.25	-	SCN-	25°C, pH 5.5	Homo sapiens
0.29	-	SCN-	25°C, pH 5.5	Bos taurus
0.52	-	3,4-dihydroxyphenylacetic acid	25°C, pH 5.5	Bos taurus
0.64	-	dopamine	25°C, pH 5.5	Homo sapiens
1.84	-	catechol	25°C, pH 5.5	Bos taurus
21.1	-	catechol	25°C, pH 5.5	Homo sapiens
21.9	-	3,4-dihydroxyphenylacetic acid	25°C, pH 5.5	Homo sapiens
136.3	-	dopamine	25°C, pH 5.5	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
purified from raw milk	Bos taurus
recombinant MPO	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
mammary gland	-	Bos taurus	-
neutrophil	neutrophilic granulocytes	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3,4-dihydroxyphenylacetic acid + H2O2	-	Homo sapiens	? + H2O	-	?
3,4-dihydroxyphenylacetic acid + H2O2	-	Bos taurus	? + H2O	-	?
catechol + H2O2	-	Homo sapiens	? + H2O	-	?
catechol + H2O2	-	Bos taurus	? + H2O	-	?
dopamine + H2O2	-	Homo sapiens	? + H2O	-	?
dopamine + H2O2	-	Bos taurus	? + H2O	-	?
SCN- + H2O2	-	Homo sapiens	OSCN- + H2O	-	?
SCN- + H2O2	-	Bos taurus	OSCN- + H2O	-	?

Synonyms

Synonyms	Comment	Organism
LPO	-	Bos taurus
recombinant human MPO	-	Homo sapiens
rhMPO	-	Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.0000001	-	dopamine	25°C, pH 5.5	Homo sapiens
0.00000016	-	SCN-	25°C, pH 5.5	Homo sapiens
0.0000016	-	dopamine	25°C, pH 5.5	Bos taurus
0.0000033	-	SCN-	25°C, pH 5.5	Bos taurus
0.000012	-	catechol	25°C, pH 5.5	Homo sapiens
0.000022	-	catechol	25°C, pH 5.5	Bos taurus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)