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Literature summary for 1.11.1.9 extracted from
- Aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells (2009), Microvasc. Res., 78, 447-452.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | aging decreases expression and activity of glutathione peroxidase-1 in human endothelial progenitor cells, increasing selenium concentration in the cell culture does not affect the protein levels of GPX1, suggesting the reduced GPX1 in old subject's endothelial progenitor cells is selenium independent | Homo sapiens |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| selenium | the enzyme contains selenium | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endothelial progenitor cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione + ROOH | - |
Homo sapiens | glutathione disulfide + ROH + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glutathione peroxidase-1 | - |
Homo sapiens |
| GPX1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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