Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.11.1.9 extracted from

  • Savaskan, N.E.; Ufer, C.; Kuehn, H.; Borchert, A.
    Molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function (2007), Biol. Chem., 388, 1007-1017.
    View publication on PubMed
Search for more literature for 1.11.1.9

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-
mitochondrion
-
 Mus musculus 5739
-
nucleus
-
 Mus musculus 5634
-

Metals/Ions

Metals/Ions Comment Organism Structure
selenium selenoprotein Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
19000
-
 isozyme c-GPx4, SDS-PAGE Mus musculus
34000
-
 isozyme n-GPx4, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q5XJZ8 fragment
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte
-
 Mus musculus
-
hippocampus
-
 Mus musculus
-
neuron
-
 Mus musculus
-
spermatocyte isozyme n-GPx-4 is specifically expressed in late spermatocytes Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + ROOH
-
 Mus musculus glutathione disulfide + ROH + H2O
-
 ?
H2O2 + GSH
-
 Mus musculus H2O + GSSG
-
 ?
additional information does not accept thioredoxin as hydrogen donor Mus musculus ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 19000, isozyme c-GPx4, SDS-PAGE Mus musculus
monomer 1 * 34000, isozyme c-GPx4, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
c-GPx4 isoform, cytosolic GPx4 Mus musculus
glutathione peroxidase 4
-
 Mus musculus
GPx4
-
 Mus musculus
m-GPx4 isoform, mitochondrial GPx4 Mus musculus
n-GPx4 isoform, nuclear GPx4 Mus musculus
PHGPX
-
 Mus musculus
phospholipid hydroperoxide glutathione peroxidase
-
 Mus musculus