Cloned (Comment) | Organism |
---|---|
CHO-K1 cells introduced with mutated TPO-MRNA | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
D574/L575del | expressed to some extent on the cell surface, prolongation in kinetics, increasing interaction with calnexin | Homo sapiens |
G533C | expressed to some extent on the cell surface, prolongation in kinetics, increasing interaction with calnexin | Homo sapiens |
G771R | expressed to some extent on the cell surface, prolongation in kinetics, increasing interaction with calnexin | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | wild-type enzyme and mutant enzymes G614A, G1687T, 1808-13del, C2083, G2401A | Homo sapiens | 5783 | - |
nuclear envelope | wild-type enzyme and mutant enzymes G614A, G1687T, 1808-13del, C2083, G2401A | Homo sapiens | 5635 | - |
plasma membrane | mutant enzymes D574/L575del, G553C and G771R expressed to varying degree on the plasma membrane. Mutant R665W shows no cell surface localization | Homo sapiens | 5886 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
thyroid peroxidase | - |
Homo sapiens |
TPQ | - |
Homo sapiens |