Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cysteine | complete inhibition at 0.05 mM, reversible by increasing I- concentration | Homo sapiens | |
histidine | - |
Homo sapiens | |
methimazol | - |
Homo sapiens | |
methionine | complete inhibition at 0.05 mM, reversible by increasing I- concentration | Homo sapiens | |
additional information | inhibited by hydrolyzed enzyme preparation, hydrolyzed bovine serum albumin and casein, guaiacol oxidation not significantly affected by amino acids | Homo sapiens | |
phenylalanine | - |
Homo sapiens | |
propylthiouracil | - |
Homo sapiens | |
tryptophan | complete inhibition at 0.05 mM, reversible by increasing I- concentration | Homo sapiens | |
tyrosine | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
7.7 | - |
I- | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
iodide + H2O2 | Homo sapiens | biosynthesis of thyroid hormones | iodine + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thyroid gland | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
guaiacol + H2O2 + I- | - |
Homo sapiens | tetraguaiacol + H2O | - |
? | |
iodide + H2O2 | - |
Homo sapiens | iodine + H2O | - |
? | |
iodide + H2O2 | biosynthesis of thyroid hormones | Homo sapiens | iodine + H2O | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Homo sapiens |