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Literature summary for 1.11.1.7 extracted from

  • Trivedi, V.; Srivastava, K.; Puri, S.K.; Maulik, P.R.; Bandyopadhyay, U.
    Purification and biochemical characterization of a heme containing peroxidase from the human parasite P. falciparum (2005), Protein Expr. Purif., 41, 154-161.
    View publication on PubMed
Search for more literature for 1.11.1.7

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.7
-
 guaiacol pH 7.2 Plasmodium falciparum

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Plasmodium falciparum 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
15000
-
 2 * 15000, SDS-PAGE Plasmodium falciparum
15118
-
 2 * 15118, MALDI-TOF-mass spectroscopy Plasmodium falciparum
30000
-
 gel filtration Plasmodium falciparum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Plasmodium falciparum as the parasite is susceptible to oxidative stress, this peroxidase may offer antioxidant role by scavenging endogenous H2O2 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Plasmodium falciparum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Plasmodium falciparum

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.08
-
-
 Plasmodium falciparum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
guaiacol + H2O2
-
 Plasmodium falciparum ?
-
 ?
additional information as the parasite is susceptible to oxidative stress, this peroxidase may offer antioxidant role by scavenging endogenous H2O2 Plasmodium falciparum ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 15000, SDS-PAGE Plasmodium falciparum
dimer 2 * 15118, MALDI-TOF-mass spectroscopy Plasmodium falciparum

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.3
-
 guaiacol pH 7.2 Plasmodium falciparum

Cofactor

Cofactor Comment Organism Structure
heme contains 2 mol of heme per mol of the enzyme. Iron of heme is in Fe-III state Plasmodium falciparum