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Literature summary for 1.11.1.28 extracted from
- Functional and evolutionary characterization of Ohr proteins in eukaryotes reveals many active homologs among pathogenic fungi (2017), Redox Biol., 12, 600-609 .
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C154S | mutant enzyme loses peroxidase activity. The enzyme shows no activity and no formation of intramolecular disulfide bond upon treatment with hydroperoxides | Pseudocercospora fijiensis |
| C87S | mutant enzyme loses peroxidase activity. The enzyme shows no activity and no formation of intramolecular disulfide bond upon treatment with hydroperoxides | Pseudocercospora fijiensis |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | the enzyme is preferentially located in mitochondrion | Pseudocercospora fijiensis | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudocercospora fijiensis | N1Q9R6 | i.e. Mycosphaerella fijiensis Mf_1 | - |
| Pseudocercospora fijiensis CIRAD86 | N1Q9R6 | i.e. Mycosphaerella fijiensis Mf_1 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cumene hydroperoxide + dihydrolipoamide | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis | 2-phenylpropan-2-ol + lipoamide | - |
? |  |
| cumene hydroperoxide + dihydrolipoamide | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis CIRAD86 | 2-phenylpropan-2-ol + lipoamide | - |
? | |
| cumene hydroperoxide + dithiothreitol | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis | 2-phenylpropan-2-ol + oxidized dithiothreitol | - |
? | |
| cumene hydroperoxide + dithiothreitol | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis CIRAD86 | 2-phenylpropan-2-ol + oxidized dithiothreitol | - |
? | |
| H2O2 + dihydrolipoamide | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis | H2O + lipoamide | - |
? | |
| H2O2 + dihydrolipoamide | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis CIRAD86 | H2O + lipoamide | - |
? | |
| H2O2 + reduced dithiothreitol | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis | H2O + oxidized dithiothreitol | - |
? | |
| H2O2 + reduced dithiothreitol | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis CIRAD86 | H2O + oxidized dithiothreitol | - |
? | |
| linoleic acid hydroperoxide + dihydrolipoamide | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis | ? + lipoamide | - |
? | |
| linoleic acid hydroperoxide + reduced dithiothreitol | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis | ? + oxidized dithiothreitol | - |
? | |
| tert-butyl hydroperoxide + dihydrolipoamide | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis | tert-butanol + lipoamide | - |
? | |
| tert-butyl hydroperoxide + reduced dithiothreitol | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis | tert-butanol + oxidized dithiothreitol | - |
? | |
| tert-butyl hydroperoxide + reduced dithiothreitol | the peroxidase activity of the enzyme (MfOhr) is supported by dithiothreitol or dihydrolipoamide, but not by beta-mercaptoethanol or glutathione. MfOhr displays preference for organic hydroperoxides (cumene hydroperoxide and tert-butyl hydroperoxide) over hydrogen peroxide. MfOhr presents extraordinary reactivity towards linoleic acid hydroperoxides | Pseudocercospora fijiensis CIRAD86 | tert-butanol + oxidized dithiothreitol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MfOhr | - |
Pseudocercospora fijiensis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Pseudocercospora fijiensis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Pseudocercospora fijiensis |
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