Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | neither tert-butyl hydroperoxide nor cumene hydroperoxide demonstrate any observable inactivation of the enzyme, even when present at concentrations as high as 60 mM | Salmonella enterica subsp. enterica serovar Typhimurium |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0014 | - |
H2O2 | in 50 mM potassium phosphate pH 7.0, at 25°C | Salmonella enterica subsp. enterica serovar Typhimurium | |
0.0045 | - |
Ethyl hydroperoxide | in 50 mM potassium phosphate pH 7.0, at 25°C | Salmonella enterica subsp. enterica serovar Typhimurium | |
0.107 | - |
cumene hydroperoxide | in 50 mM potassium phosphate pH 7.0, at 25°C | Salmonella enterica subsp. enterica serovar Typhimurium | |
0.238 | - |
tert-butyl hydroperoxide | in 50 mM potassium phosphate pH 7.0, at 25°C | Salmonella enterica subsp. enterica serovar Typhimurium |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Salmonella enterica subsp. enterica serovar Typhimurium | P0A251 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cumene hydroperoxide + reduced thioredoxin | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 2-phenylpropan-2-ol + oxidized thioredoxin + H2O | - |
? | |
ethyl hydroperoxide + reduced thioredoxin | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ? + oxidized thioredoxin | - |
? | |
H2O2 + reduced thioredoxin | - |
Salmonella enterica subsp. enterica serovar Typhimurium | H2O + oxidized thioredoxin | - |
? | |
linoleic acid hydroperoxide + reduced thioredoxin | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ? + oxidized thioredoxin | - |
? | |
tert-butyl hydroperoxide + reduced thioredoxin | - |
Salmonella enterica subsp. enterica serovar Typhimurium | tert-butanol + oxidized thioredoxin + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
2-Cys Prx | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
AhpC | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
alkyl hydroperoxide reductase C component | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
52 | - |
cumene hydroperoxide | in 50 mM potassium phosphate pH 7.0, at 25°C | Salmonella enterica subsp. enterica serovar Typhimurium | |
52.4 | - |
H2O2 | in 50 mM potassium phosphate pH 7.0, at 25°C | Salmonella enterica subsp. enterica serovar Typhimurium | |
52.7 | - |
Ethyl hydroperoxide | in 50 mM potassium phosphate pH 7.0, at 25°C | Salmonella enterica subsp. enterica serovar Typhimurium | |
54.7 | - |
tert-butyl hydroperoxide | in 50 mM potassium phosphate pH 7.0, at 25°C | Salmonella enterica subsp. enterica serovar Typhimurium |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thioredoxin | - |
Salmonella enterica subsp. enterica serovar Typhimurium |