Crystallization (Comment) | Organism |
---|---|
hanging drop vapour diffusion method with 100 mM citrate (pH 4.6) and 10% polyethylene glycol | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C83S | increased activity compared to wild type Prx1 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
H2O2 | highly susceptible to inactivation by H2O2; highly susceptible to inactivation by H2O2 | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43630 | - |
Prx2, Q-TOF mass spectrometry | Homo sapiens |
219700 | - |
Prx1, Q-TOF mass spectrometry | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P32119 | - |
- |
Homo sapiens | Q06830 | - |
- |
Purification (Comment) | Organism |
---|---|
DEAE-Sepharose column chromatography, SP-Sepharose column chromatography, and Superdex 200 gel filtration | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2O2 + reduced dithiothreitol | - |
Homo sapiens | H2O + oxidized dithiothreitol | - |
? |
Subunits | Comment | Organism |
---|---|---|
decamer | Prx1, X-ray crystallography | Homo sapiens |
dimer | Prx2, X-ray crystallography | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
peroxiredoxin 1 | - |
Homo sapiens |
peroxiredoxin 2 | - |
Homo sapiens |
Prx1 | - |
Homo sapiens |
Prx2 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thioredoxin | - |
Homo sapiens |