Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C152S | mutant enzyme shows no detectable thioredoxin-dependent peroxidase activity | Homo sapiens |
C48S | mutant enzyme shows no detectable thioredoxin-dependent peroxidase activity | Homo sapiens |
C73S | mutation has no effect on activity | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | the Km-value for H2O2 is below 0.02 mM | Homo sapiens | |
0.001 | - |
thioredoxin | pH 7.0, 37°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
peroxisome | - |
Homo sapiens | 5777 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
17000 | - |
2 * 17000, SDS-PAGE | Homo sapiens |
17030 | - |
2 * 17030, calculation from nucleotide sequence | Homo sapiens |
34000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2O2 + reduced thioredoxin | - |
Homo sapiens | H2O + oxidized thioredoxin | - |
? | |
additional information | no activity with glutaredoxin or glutathione | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 17000, SDS-PAGE | Homo sapiens |
dimer | 2 * 17030, calculation from nucleotide sequence | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
PrxV | - |
Homo sapiens |