Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.11.1.18 extracted from

  • Biswal, D.; Pramanik, N.; Drew, M.; Jangra, N.; Maurya, M.; Kundu, M.; Sil, P.; Chakrabarti, S.
    Synthesis, crystal structure, DFT calculations, protein interaction, anticancer potential and bromoperoxidase mimicking activity of oxidoalkoxidovanadium(V) complexes (2019), New J. Chem., 43, 17783-17800 .
No PubMed abstract available

Protein Variants

Protein Variants Comment Organism
additional information synthesis, crystal structure, DFT calculations, protein interaction, anticancer potential and bromoperoxidase mimicking activity of oxidoalkoxidovanadium(V) complexes: DFT calculations, protein interaction analysis, circular dichroism study, anticancer activity determination with MCF-7 cells, and determination of mitochondrial membrane potential (MMP) as well as intracellular reactive oxygen species (ROS) production, detailed overview Ascophyllum nodosum

Metals/Ions

Metals/Ions Comment Organism Structure
Vanadium
-
Ascophyllum nodosum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RH + Br- + H2O2 + H+ Ascophyllum nodosum
-
RBr + 2 H2O
-
?

Organism

Organism UniProt Comment Textmining
Ascophyllum nodosum P81701
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information vanadium containing bromoperoxidase mimicking (structural and/or functional) activities of vanadium(V) complexes has been reported by several groups in which the active site contains vanadium(V) coordinated to O/N donor ligands. Vanadium(V) complexes catalyze the oxidative bromination of organic substrates into useful halogenated organic compounds in the presence of halide and H2O2 in mild acid medium, just like natural VBrPO enzymes and hence, these are considered as models for VBrPO enzymes. Synthesis, crystal structure, DFT calculations, protein interaction, anticancer potential and bromoperoxidase mimicking activity of oxidoalkoxidovanadium(V) complexes: DFT calculations, protein interaction analysis, circular dichroism study, anticancer activity determination with MCF-7 cells, and determination of mitochondrial membrane potential (MMP) as well as intracellular reactive oxygen species (ROS) production, detailed overview Ascophyllum nodosum ?
-
-
RH + Br- + H2O2 + H+
-
Ascophyllum nodosum RBr + 2 H2O
-
?

Synonyms

Synonyms Comment Organism
V-BPO
-
Ascophyllum nodosum
vanadium-dependent bromoperoxidase
-
Ascophyllum nodosum
VBrPO
-
Ascophyllum nodosum

Cofactor

Cofactor Comment Organism Structure
vanadate cofactor
-
Ascophyllum nodosum