Protein Variants | Comment | Organism |
---|---|---|
additional information | synthesis, crystal structure, DFT calculations, protein interaction, anticancer potential and bromoperoxidase mimicking activity of oxidoalkoxidovanadium(V) complexes: DFT calculations, protein interaction analysis, circular dichroism study, anticancer activity determination with MCF-7 cells, and determination of mitochondrial membrane potential (MMP) as well as intracellular reactive oxygen species (ROS) production, detailed overview | Ascophyllum nodosum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Vanadium | - |
Ascophyllum nodosum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
RH + Br- + H2O2 + H+ | Ascophyllum nodosum | - |
RBr + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ascophyllum nodosum | P81701 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | vanadium containing bromoperoxidase mimicking (structural and/or functional) activities of vanadium(V) complexes has been reported by several groups in which the active site contains vanadium(V) coordinated to O/N donor ligands. Vanadium(V) complexes catalyze the oxidative bromination of organic substrates into useful halogenated organic compounds in the presence of halide and H2O2 in mild acid medium, just like natural VBrPO enzymes and hence, these are considered as models for VBrPO enzymes. Synthesis, crystal structure, DFT calculations, protein interaction, anticancer potential and bromoperoxidase mimicking activity of oxidoalkoxidovanadium(V) complexes: DFT calculations, protein interaction analysis, circular dichroism study, anticancer activity determination with MCF-7 cells, and determination of mitochondrial membrane potential (MMP) as well as intracellular reactive oxygen species (ROS) production, detailed overview | Ascophyllum nodosum | ? | - |
- |
|
RH + Br- + H2O2 + H+ | - |
Ascophyllum nodosum | RBr + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
V-BPO | - |
Ascophyllum nodosum |
vanadium-dependent bromoperoxidase | - |
Ascophyllum nodosum |
VBrPO | - |
Ascophyllum nodosum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
vanadate cofactor | - |
Ascophyllum nodosum |