Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-[[4-(diethylamino)butyl]amino]-10-methoxy-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-7,10-dimethoxy-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-7-hydroxy-10-methoxy-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-7-hydroxy-8,9-dimethoxy-6H-imidazo[4,5,1-de]acridin-6-one | most potent inhibitor of NQO2 | Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-8-hydroxy-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-8-methoxy-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-8-methoxy-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(diethylamino)butyl]amino]-9-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(dimethylamino)butyl]amino]-1-ethyl-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(dimethylamino)butyl]amino]-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(dimethylamino)butyl]amino]-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(dimethylamino)butyl]amino]-8-hydroxy-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[4-(dimethylamino)butyl]amino]-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[6-(diethylamino)hexyl]amino]-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
5-[[6-(dimethylamino)hexyl]amino]-6H-imidazo[4,5,1-de]acridin-6-one | - |
Homo sapiens | |
NSC637991 | - |
Homo sapiens | |
NSC637992 | - |
Homo sapiens | |
NSC637993 | - |
Homo sapiens | |
NSC637994 | - |
Homo sapiens | |
NSC645808 | - |
Homo sapiens | |
NSC645809 | - |
Homo sapiens | |
NSC645811 | - |
Homo sapiens | |
NSC645812 | - |
Homo sapiens | |
NSC645831 | - |
Homo sapiens | |
NSC645833 | - |
Homo sapiens | |
NSC645834 | - |
Homo sapiens | |
NSC645835 | - |
Homo sapiens | |
NSC645836 | - |
Homo sapiens | |
NSC660838 | - |
Homo sapiens | |
NSC660839 | - |
Homo sapiens | |
NSC660840 | - |
Homo sapiens | |
NSC660841 | most potent inhibitor of NQO2 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HCT-116 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
NQO2 | - |
Homo sapiens |
NRH:quinone oxidoreductase 2 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000006 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC660841 | |
0.000006 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-7-hydroxy-8,9-dimethoxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000009 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-8-methoxy-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000009 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC637993 | |
0.000016 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-8-hydroxy-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000016 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC637992 | |
0.000017 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-7,10-dimethoxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000017 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC660839 | |
0.000031 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-7-hydroxy-10-methoxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000031 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC660840 | |
0.00005 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(dimethylamino)butyl]amino]-8-hydroxy-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one | |
0.00005 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC637991 | |
0.000099 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-10-methoxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000099 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC660838 | |
0.000148 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000148 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645809 | |
0.000172 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[6-(dimethylamino)hexyl]amino]-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000172 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645836 | |
0.000296 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(dimethylamino)butyl]amino]-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000296 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645808 | |
0.000323 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(dimethylamino)butyl]amino]-1-methyl-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000323 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645834 | |
0.000427 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000427 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645831 | |
0.000597 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[6-(diethylamino)hexyl]amino]-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000597 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC637994 | |
0.000693 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(dimethylamino)butyl]amino]-1-ethyl-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000693 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645835 | |
0.00083 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(dimethylamino)butyl]amino]-6H-imidazo[4,5,1-de]acridin-6-one | |
0.00083 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645833 | |
0.000953 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-9-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.000953 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645811 | |
0.001 | - |
pH and temperature not specified in the publication | Homo sapiens | 5-[[4-(diethylamino)butyl]amino]-8-methoxy-6H-imidazo[4,5,1-de]acridin-6-one | |
0.001 | - |
pH and temperature not specified in the publication | Homo sapiens | NSC645812 |