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Literature summary for 1.10.3.5 extracted from

  • Morgan, L.R.; Weimorts, D.M.; Aubert, C.C.
    Oxidation of 3-hydroxyanthranilic acid by a soluble liver fraction from poikilothermic vertebrates (1965), Biochim. Biophys. Acta, 100, 393-402.
    View publication on PubMed
Search for more literature for 1.10.3.5

Inhibitors

Inhibitors Comment Organism Structure
alpha,alpha'-dipyridyl
-
 Rattus norvegicus
CN-
-
 Rattus norvegicus
Dopa
-
 Rattus norvegicus
EDTA
-
 Rattus norvegicus
Fe2+
-
 Rattus norvegicus
N3-
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 3-hydroxyanthranilic acid + 2 O2 Rattus norvegicus
-
 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Alligator mississippiensis
-
 american alligator
-
Amphiuma means
-
 salamander, two-toad amphiuma
-
Chelydra serpentina
-
 snapping turtle
-
Felis catus
-
 cat
-
Pseudemys concinna floridana
-
 turtle, red-eared slider
-
Rattus norvegicus
-
-
-
Rhinella marina
-
 cane toad
-
Streptomyces antibioticus
-
-
-
Terrapene carolina
-
 eastern box turtle
-
Trachemys scripta
-
 turtle, florida cooter
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-
liver
-
 Felis catus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.141
-
-
 Rattus norvegicus

Storage Stability

Storage Stability Organism
-20°C, can be stored for several months with no detectable inactivation Rattus norvegicus
20°C, shows little loss of activity at room temperature Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 3-hydroxyanthranilic acid + 2 O2
-
 Rattus norvegicus 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Felis catus 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Rhinella marina 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Streptomyces antibioticus 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Trachemys scripta 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Alligator mississippiensis 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Amphiuma means 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Chelydra serpentina 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Pseudemys concinna floridana 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
2 3-hydroxyanthranilic acid + 2 O2
-
 Terrapene carolina 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
3-hydroxy-4-methylanthranilic acid + O2
-
 Rattus norvegicus actinocin
-
 ?
3-hydroxy-4-methylanthranilic acid + O2
-
 Streptomyces antibioticus actinocin
-
 ?
3-hydroxy-L-kynurenine + O2
-
 Rattus norvegicus (2S)-2-amino-4-(6-imino-5-oxocyclohexa-1,3-dien-1yl)-4-oxo-butanoic acid + H2O2
-
 ?
ethyl-3-hydroxyanthranilate + O2
-
 Rattus norvegicus ?
-
 ?
additional information 2-amino-3-hydroxytoluene is no substrate Rattus norvegicus ?
-
 ?
o-aminophenol + O2
-
 Rattus norvegicus phenoxazinone + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
o-aminophenol:O2 oxidoreductase
-
 Streptomyces antibioticus
phenoxazine-synthetase
-
 Streptomyces antibioticus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2 7.4
-
 Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
6.5 8.5
-
 Rattus norvegicus