Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Clonorchis sinensis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diethyldithiocarbamic acid | - |
Clonorchis sinensis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.6 | 2 | L-Dopa | at pH 7.0 and 37°C | Clonorchis sinensis | |
23.52 | - |
catechol | at pH 7.0 and 37°C | Clonorchis sinensis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
copper | contains copper | Clonorchis sinensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydroxyphenylalanine + O2 | Clonorchis sinensis | - |
dihydroxyphenylalanine quinone + H2O | - |
? | |
L-tyrosine + O2 | Clonorchis sinensis | - |
dihydroxyphenylalanine + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clonorchis sinensis | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Clonorchis sinensis |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography | Clonorchis sinensis |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
egg | intrauterine immature egg | Clonorchis sinensis | - |
vitelline gland | - |
Clonorchis sinensis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-methylhydroquinone + O2 | low activity | Clonorchis sinensis | ? | - |
? | |
4-methylcatechol + O2 | highest activity | Clonorchis sinensis | ? | - |
? | |
catechol + O2 | - |
Clonorchis sinensis | ? | - |
? | |
dihydroxyphenylalanine + O2 | - |
Clonorchis sinensis | dihydroxyphenylalanine quinone + H2O | - |
? | |
dopamine + O2 | - |
Clonorchis sinensis | ? | - |
? | |
hydroquinone + O2 | low activity | Clonorchis sinensis | ? | - |
? | |
L-DOPA + O2 | - |
Clonorchis sinensis | ? | - |
? | |
L-tyrosine + O2 | - |
Clonorchis sinensis | dihydroxyphenylalanine + H2O | - |
? | |
additional information | the enzyme shows minimal activity toward monophenol compounds such as tyramine, tyrosine and tyrosine methyl ester | Clonorchis sinensis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TYR3 | isoform | Clonorchis sinensis |
tyrosinase | - |
Clonorchis sinensis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Clonorchis sinensis |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is essential for Clonorchis sinensis reproduction | Clonorchis sinensis |