Any feedback?
Literature summary for 1.1.99.B1 extracted from
- Flavin adenine dinucleotide-dependent 4-phospho-D-erythronate dehydrogenase is responsible for the 4-phosphohydroxy-L-threonine pathway in vitamin B6 biosynthesis in Sinorhizobium meliloti (2006), J. Bacteriol., 188, 4635-4645.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 53000 | - |
SDS-PAGE | Sinorhizobium meliloti |
| 53190 | - |
predicted from the pdxR DNA sequence | Sinorhizobium meliloti |
| 106000 | - |
gel filtration chromatography | Sinorhizobium meliloti |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sinorhizobium meliloti | - |
formerly Rhizobium meliloti, strain IFO 14782 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Q Sepharose FF column chromatography and Sephadex LH 20 column chromatography | Sinorhizobium meliloti |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.946 | - |
0.091 mM DCIP and 0.00024 mg purified enzyme in 33 mM potassium phosphate buffer at pH 7.0 | Sinorhizobium meliloti |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-phospho-D-erythronate + 2,6-dichloroindophenol | - |
Sinorhizobium meliloti | 3-hydroxy-4-phosphohydroxy-alpha-ketobutyrate + reduced 2,6-dichloroindophenol | - |
? |  |
| 4-phospho-D-erythronate + FAD | - |
Sinorhizobium meliloti | 3-hydroxy-4-phosphohydroxy-alpha-ketobutyrate + FADH2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | 2 * 53000, SDS-PAGE | Sinorhizobium meliloti |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 4PE dehydrogenase | - |
Sinorhizobium meliloti |
| 4PE oxidoreductase | - |
Sinorhizobium meliloti |
| flavin adenine dinucleotide-dependent 4-phospho-D-erythronate dehydrogenase | - |
Sinorhizobium meliloti |
| pdxR-encoded 4PE dehydrogenase | - |
Sinorhizobium meliloti |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Sinorhizobium meliloti | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2026.1 (March 2026)
Legal
Curated at
Member of
![DSMZ Digital Diversity]()
![Global Core Biodata Resource]()
![ELIXIR Core Data Resource]()
![German Network for Bioinformatics Infrastructure]()
