Literature summary for 1.1.99.41 extracted from

Edge, A.; Qu, Y.; Easson, M.L.A.E.; Thamm, A.M.K.; Kim, K.H.; De Luca, V.
A tabersonine 3-reductase Catharanthus roseus mutant accumulates vindoline pathway intermediates (2018), Planta, 247, 155-169 .

Search for more literature for 1.1.99.41

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21-(DE3) cells	Catharanthus roseus

Protein Variants

Protein Variants	Comment	Organism
H189Y	the mutation diminishes the activity of the enzyme by 95%	Catharanthus roseus
T305T	inactive	Catharanthus roseus

Organism

Organism	UniProt	Comment	Textmining
Catharanthus roseus	A0A161CAI1	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-NTA column chromatography	Catharanthus roseus

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Catharanthus roseus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
16-methoxytabersonine + NADPH + H+	-	Catharanthus roseus	3-hydroxy-16-methoxy-2,3-dihydrotabersonine	-	?
tabersonine + NADPH + H+	-	Catharanthus roseus	2,3-dihydro-3-hydroxytabersonine + NADP+	-	?

Synonyms

Synonyms	Comment	Organism
T3R	-	Catharanthus roseus
tabersonine 3-reductas	-	Catharanthus roseus

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Release 2023.1 (January 2023)