Literature summary for 1.1.98.7 extracted from

Fang, Q.; Peng, J.; Dierks, T.
Post-translational formylglycine modification of bacterial sulfatases by the radical S-adenosylmethionine protein AtsB (2004), J. Biol. Chem., 279, 14570-14578.

Search for more literature for 1.1.98.7

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3)	Klebsiella pneumoniae

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
periplasm	-	Klebsiella pneumoniae	-	-

Organism

Organism	UniProt	Comment	Textmining
Klebsiella pneumoniae	Q9X758	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the enzyme converts a serine residue of arylsulfatase into a 3-oxo-L-alanine residue. The post-translational modification of sulfatases, i.e. the creation of a 3-oxo-L-alanine (i.e. Calpha-formylglycine) residue from a cysteine or serine is vital for the proper function of sulfatases	Klebsiella pneumoniae	?	-	?
[arylsulfatase]-L-serine + S-adenosyl-L-methionine + reduced acceptor	-	Klebsiella pneumoniae	[arylsulfatase]-3-oxo-L-alanine + L-methionine + 5'-deoxyadenosine + acceptor + H2O	-	?

Synonyms

Synonyms	Comment	Organism
anaerobic sulfatase-maturating enzyme	-	Klebsiella pneumoniae
AtsB	-	Klebsiella pneumoniae

General Information

General Information	Comment	Organism
metabolism	involved in the pathway of sulfatase oxidation	Klebsiella pneumoniae

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Release 2023.1 (January 2023)