Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ribonucleoside 5'-triphosphate + formate | - |
Escherichia coli | 2'-deoxyribonucleoside 5'-triphosphate + CO2 + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
class III ribonucleoside-triphosphate reductase | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
physiological function | during the reduction of ribonucleotides with [3H]formate tritium appears in water and not in the product deoxyribonucleotide. In D2O, deuterium replaces the OH-group at carbon-2' with retention of configuration. Class I, II and class III enzymes catalyze identical reactions. Members of the three classes of reductases apparently use the same chemical mechanism in spite of having completely different protein structures | Escherichia coli |