Crystallization (Comment) | Organism |
---|---|
crystal structure of the enzyme in the native state and in complexes with the four inhibitors p-cresol, isoeugenol, 2-nitro-p-cresol and heptenyl-phenol | Penicillium simplicissimum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Nitro-p-cresol | - |
Penicillium simplicissimum | |
4-(1-Heptenyl)-phenol | the crystal structure of the enzyme in complex with the inhibitor shows that the catalytic cavity is completely filled by the inhibitor | Penicillium simplicissimum | |
isoeugenol | - |
Penicillium simplicissimum | |
p-Cresol | - |
Penicillium simplicissimum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Penicillium simplicissimum | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
Vanillyl alcohol + O2 = vanillin + H2O2 | the shape of the active-site cavity controls substrate specificity by providing a size exclusion mechanism. Inside the cavity the substrate aromatic ring is positioned at an angle of 18° to the flavin ring | Penicillium simplicissimum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | protein-bound | Penicillium simplicissimum |