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Literature summary for 1.1.3.17 extracted from

  • Gadda, G.; Powell, N.L.; Menon, P.
    The trimethylammonium headgroup of choline is a major determinant for substrate binding and specificity in choline oxidase (2004), Arch. Biochem. Biophys., 430, 264-273.
    View publication on PubMed
Search for more literature for 1.1.3.17

Inhibitors

Inhibitors Comment Organism Structure
(2-amino-ethyl)trimethylammonim chloride
-
 Arthrobacter globiformis
allyltrimethylammonium chloride
-
 Arthrobacter globiformis
diethylmethylamine
-
 Arthrobacter globiformis
Dimethylamine
-
 Arthrobacter globiformis
dimethylethylamine
-
 Arthrobacter globiformis
ethylamine
-
 Arthrobacter globiformis
glycine betaine
-
 Arthrobacter globiformis
methylamine
-
 Arthrobacter globiformis
methylethylamine
-
 Arthrobacter globiformis
N,N-dimethylglycine
-
 Arthrobacter globiformis
N-methylglycine
-
 Arthrobacter globiformis
tetramethylamine
-
 Arthrobacter globiformis
trimethylamine
-
 Arthrobacter globiformis
trimethylethylammonium chloride
-
 Arthrobacter globiformis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.32
-
 N,N-dimethylethanolamine pH 8.0, 25°C Arthrobacter globiformis
0.43
-
 choline pH 8.0, 25°C Arthrobacter globiformis
0.52
-
 N-Methylethanolamine pH 8.0, 25°C Arthrobacter globiformis
1.01
-
 3,3-dimethyl-1-butanol pH 8.0, 25°C Arthrobacter globiformis

Organism

Organism UniProt Comment Textmining
Arthrobacter globiformis
-
 strain ATCC 8010
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,3-dimethyl-butanol + O2
-
 Arthrobacter globiformis 3,3-dimethylbutanal + H2O2
-
 ?
betaine aldehyde + O2 + H2O
-
 Arthrobacter globiformis betaine + H2O2
-
 ?
choline + O2
-
 Arthrobacter globiformis betaine aldehyde + H2O2
-
 ?
N,N-dimethylethanolamine + O2
-
 Arthrobacter globiformis N,N-dimethylethanalamine + H2O2
-
 ?
N-methylethanolamine + O2
-
 Arthrobacter globiformis N-methylethanalamine + H2O2
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.37
-
 N-Methylethanolamine pH 8.0, 25°C Arthrobacter globiformis
5.9
-
 N,N-dimethylethanolamine pH 8.0, 25°C Arthrobacter globiformis
8
-
 3,3-dimethyl-1-butanol pH 8.0, 25°C Arthrobacter globiformis
86
-
 choline pH 8.0, 25°C Arthrobacter globiformis

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4
-
 trimethylamine pH 8.0, 25°C Arthrobacter globiformis
5
-
 diethylmethylamine pH 8.0, 25°C Arthrobacter globiformis
6
-
 Dimethylamine pH 8.0, 25°C Arthrobacter globiformis
8
-
 methylethylamine pH 8.0, 25°C Arthrobacter globiformis
9
-
 dimethylethylamine pH 8.0, 25°C Arthrobacter globiformis
9
-
 (2-amino-ethyl)trimethylammonim chloride pH 8.0, 25°C Arthrobacter globiformis
11
-
 tetramethylamine pH 8.0, 25°C Arthrobacter globiformis
11
-
 ethylamine pH 8.0, 25°C Arthrobacter globiformis
13
-
 trimethylethylammonium chloride pH 8.0, 25°C Arthrobacter globiformis
15
-
 glycine betaine pH 8.0, 25°C Arthrobacter globiformis
15
-
 allyltrimethylammonium chloride pH 8.0, 25°C Arthrobacter globiformis
26
-
 methylamine pH 8.0, 25°C Arthrobacter globiformis
57
-
 N,N-dimethylglycine pH 8.0, 25°C Arthrobacter globiformis
405
-
 N-methylglycine pH 8.0, 25°C Arthrobacter globiformis