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Literature summary for 1.1.3.15 extracted from

  • Zhou, F.; Wu, G.; Deng, W.; Pu, Y.; Wei, C.; Li, Y.
    Interaction of rice dwarf virus outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8 (2007), FEBS Lett., 581, 34-40.
    View publication on PubMed

Application

Application Comment Organism
molecular biology the interaction of capsid protein P8 with the GOX of host cells leads to translocation of capsid protein P8 into peroxisomes. The interaction between capsid protein P8 and GOX plays important roles in Rice dwarf phytoreovirus targeting into the replication site of host cells Oryza sativa

Cloned(Commentary)

Cloned (Comment) Organism
co-expression of the enzyme with the Rice dwarf virus, RDV, outer capsid P8 protein in Spodoptera frugiperda cells, the localization of P8 in Spodoptera frugiperda cells changed from diffuse to discrete, punctuate inclusions during expression from 24 to 48 h post inoculation, coexpression of GOX with P8 may target P8 into peroxisomes, which serve as replication sites for a number of viruses Oryza sativa

Protein Variants

Protein Variants Comment Organism
additional information co-expression of GOX with capsid protein P8 targets capsid protein P8 into peroxisomes: time course analysis demonstrates that the localization of capsid protein P8 in peroxisomes of Spodoptera frugiperda cells, co-expressing capsid protein P8 and GOX, changes from diffuse to discrete, punctuate inclusions during expression from 24 to 48 h post inoculation Oryza sativa
additional information yeast two-hybrid and co-immunoprecipitation assays indicate that capsid protein P8, an outer capsid protein of Rice dwarf phytoreovirus (RDV), interacts with rice glycolate oxidase (GOX) Oryza sativa

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome
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Oryza sativa 5777
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peroxisome confocal immunofluorescence microscopy reveals that capsid protein P8 is colocalized with GOX in peroxisomes Oryza sativa 5777
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Oryza sativa interaction of Rice dwarf virus, RDV, outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8, GOX may play important roles in RDV targeting into the replication site of host cells, overview ?
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Organism

Organism UniProt Comment Textmining
Oryza sativa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information interaction of Rice dwarf virus, RDV, outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8, GOX may play important roles in RDV targeting into the replication site of host cells, overview Oryza sativa ?
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?

Synonyms

Synonyms Comment Organism
glycolate oxidase
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Oryza sativa
GOX
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Oryza sativa