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Literature summary for 1.1.2.8 extracted from

  • Wehrmann, M.; Billard, P.; Martin-Meriadec, A.; Zegeye, A.; Klebensberger, J.
    Functional role of lanthanides in enzymatic activity and transcriptional regulation of pyrroloquinoline quinone-dependent alcohol dehydrogenases in Pseudomonas putida KT2440 (2017), mBio, 8, e00570-17 .
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.085
-
ethanol pH 8.0, 30┬░C Pseudomonas putida
0.115
-
2-phenylethanol pH 8.0, 30┬░C Pseudomonas putida
0.899
-
acetaldehyde pH 8.0, 30┬░C Pseudomonas putida

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ the enzyme is only active in the presence of Ca2+ Pseudomonas putida

Organism

Organism UniProt Comment Textmining
Pseudomonas putida Q88JH5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-butanol + phenazine methosulfate
-
Pseudomonas putida butanal + reduced phenazine methosulfate
-
?
1-hexanol + phenazine methosulfate
-
Pseudomonas putida hexanal + reduced phenazine methosulfate
-
?
1-octanol + phenazine methosulfate
-
Pseudomonas putida octanal + reduced phenazine methosulfate
-
?
2,3-butanediol + phenazine methosulfate
-
Pseudomonas putida ? + reduced phenazine methosulfate
-
?
2-butanol + phenazine methosulfate
-
Pseudomonas putida butan-2-one + reduced phenazine methosulfate
-
?
2-phenylethanol + phenazine methosulfate
-
Pseudomonas putida phenylacetaldehyde + reduced phenazine methosulfate
-
?
acetaldehyde + phenazine methosulfate
-
Pseudomonas putida ? + reduced phenazine methosulfate
-
?
butyraldehyde + phenazine methosulfate
-
Pseudomonas putida ? + reduced phenazine methosulfate
-
?
cinnamyl alcohol + phenazine methosulfate
-
Pseudomonas putida cinnamyl aldehyde + reduced phenazine methosulfate
-
?
ethanol + phenazine methosulfate
-
Pseudomonas putida acetaldehyde + reduced phenazine methosulfate
-
?
ethanolamine + phenazine methosulfate
-
Pseudomonas putida ? + reduced phenazine methosulfate
-
?
farnesol + phenazine methosulfate
-
Pseudomonas putida farnesal + reduced phenazine methosulfate
-
?
hexanal + phenazine methosulfate
-
Pseudomonas putida ? + reduced phenazine methosulfate
-
?
methanol + phenazine methosulfate
-
Pseudomonas putida formaldehyde + reduced phenazine methosulfate
-
?
octanal + phenazine methosulfate
-
Pseudomonas putida ? + reduced phenazine methosulfate
-
?

Synonyms

Synonyms Comment Organism
Ca2+-dependent PQQ-ADH
-
Pseudomonas putida
PedE
-
Pseudomonas putida
pyrroloquinoline quinone-dependent alcohol dehydrogenases
-
Pseudomonas putida

General Information

General Information Comment Organism
physiological function functional redundancy and inverse regulation of PedE (Ca2+-dependent PQQ-ADH) and PedH (lanthanide-dependent PQQ-ADH) represent an adaptive strategy of Pseudomonas putida KT2440 to optimize growth with volatile alcohols in response to the availability of different lanthanides Pseudomonas putida

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.007
-
acetaldehyde pH 8.0, 30┬░C Pseudomonas putida
0.051
-
2-phenylethanol pH 8.0, 30┬░C Pseudomonas putida
0.081
-
ethanol pH 8.0, 30┬░C Pseudomonas putida