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Literature summary for 1.1.2.4 extracted from

  • Karkovska, M.; Smutok, O.; Gonchar, M.
    Laboratory prototype of bioreactor for oxidation of toxic D-lactate using yeast cells overproducing D-lactate cytochrome c oxidoreductase (2016), BioMed Res. Int., 2016, 4652876 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene DLD1, 6fold overexpression of DLDH under the strong constitutive promoter prAOX in Hansenula polymorpha strain DELTAcyb2 tr6, a strain with impairment in glucose repression of AOX promoter and devoid of catalase and L-lactate-cytochrome c oxidoreductase activities Ogataea angusta

Protein Variants

Protein Variants Comment Organism
additional information overexpression of DLDH coupling with the deletion of L-lactate-cytochrome c oxidoreductase activity opens possibility for usage of the strain as a base for construction of bioreactor for removing toxic D-lactate from fermented products due to oxidation to nontoxic pyruvate. Construction and evaluation of a bioreactor for oxidation of toxic D-lactate using yeast cells overproducing D-lactate cytochrome c oxidoreductase, using permeabilized cells and alginate gel. The efficiency of enzymatic oxidation of D-lactate by the bioreactor prototype tightly depends on flow rate through the column Ogataea angusta

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Ogataea angusta 5739
-

Organism

Organism UniProt Comment Textmining
Ogataea angusta W1QLN6
-
-
Ogataea angusta tr6 W1QLN6
-
-

Synonyms

Synonyms Comment Organism
D-lactate cytochrome c oxidoreductase
-
Ogataea angusta
D-lactate dehydrogenase (cytochrome)
-
Ogataea angusta
D-lactate: cytochrome c oxidoreductase
-
Ogataea angusta
DLD1
-
Ogataea angusta
DLDH
-
Ogataea angusta

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
20
-
assay at, in permeabilized cells Ogataea angusta

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
assay at Ogataea angusta