Application | Comment | Organism |
---|---|---|
synthesis | the enzyme can be used for stereospecific interconversion of (R)-1-phenylethanol and (S)-1-phenylethanol via the oxoform together with the (S)-specific secondary alcohol dehydrogenase using whole cells as biocatalysts that include the required cofactor regenration system, method, overview. Optically pure secondary alcohols are widely used in pharmaceuticals, flavors, agricultural chemicals and specialty materials | Microbacterium oxydans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-1-phenylethanol + NAD+ | Microbacterium oxydans | - |
acetophenone + NADH + H+ | - |
r | |
(R)-1-phenylethanol + NAD+ | Microbacterium oxydans ECU2010 | - |
acetophenone + NADH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Microbacterium oxydans | - |
- |
- |
Microbacterium oxydans ECU2010 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-1-phenylethanol + NAD+ | - |
Microbacterium oxydans | acetophenone + NADH + H+ | - |
r | |
(R)-1-phenylethanol + NAD+ | - |
Microbacterium oxydans ECU2010 | acetophenone + NADH + H+ | - |
r | |
additional information | the enzyme catalyzes stereoselective oxidation of (R)-secondary alcohols to corresponding ketones | Microbacterium oxydans | ? | - |
? | |
additional information | the enzyme catalyzes stereoselective oxidation of (R)-secondary alcohols to corresponding ketones | Microbacterium oxydans ECU2010 | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Microbacterium oxydans | |
NADH | - |
Microbacterium oxydans |