Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.B3 extracted from

  • Li, Y.; Xu, J.; Xu, Y.
    Deracemization of aryl secondary alcohols via enantioselective oxidation and stereoselective reduction with tandem whole-cell biocatalysts (2010), J. Mol. Catal. B, 64, 48-52.
No PubMed abstract available

Application

Application Comment Organism
synthesis the enzyme can be used for stereospecific interconversion of (R)-1-phenylethanol and (S)-1-phenylethanol via the oxoform together with the (R)-specific secondary alcohol dehydrogenase using whole cells as biocatalysts that include the required cofactor regenration system, method, overview. Optically pure secondary alcohols are widely used in pharmaceuticals, flavors, agricultural chemicals and specialty materials Rhodotorula sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-1-phenylethanol + NAD+ Rhodotorula sp.
-
acetophenone + NADH + H+
-
r
(S)-1-phenylethanol + NAD+ Rhodotorula sp. AS2.2241
-
acetophenone + NADH + H+
-
r

Organism

Organism UniProt Comment Textmining
Rhodotorula sp.
-
-
-
Rhodotorula sp. AS2.2241
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-1-phenylethanol + NAD+
-
Rhodotorula sp. acetophenone + NADH + H+
-
r
(S)-1-phenylethanol + NAD+
-
Rhodotorula sp. AS2.2241 acetophenone + NADH + H+
-
r
additional information the enzyme catalyzes stereoselective oxidation of (S)-secondary alcohols to corresponding ketones Rhodotorula sp. ?
-
?
additional information the enzyme catalyzes stereoselective oxidation of (S)-secondary alcohols to corresponding ketones Rhodotorula sp. AS2.2241 ?
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Rhodotorula sp.