Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(2,4-dichlorophenyl)-2-morpholino-2-thioxoethan-1-one | - |
Homo sapiens | |
1-(4-chlorophenyl)-2-morpholino-2-thioxoethan-1-one | - |
Homo sapiens | |
2-(4-methylpiperidin-1-yl)-1-phenyl-2-thioxoethan-1-one | - |
Homo sapiens | |
2-morpholino-1-phenyl-2-thioxoethan-1-one | - |
Homo sapiens | |
morpholino(phenyl)methanethione | - |
Homo sapiens | |
N-morpholinobenzenesulfonamide | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0304 | - |
NAD+ | pH 8.5, temperature not specified in the publication | Homo sapiens | |
0.294 | - |
3-phospho-D-glycerate | pH 8.5, temperature not specified in the publication | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O43175 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-phospho-D-glycerate + NAD+ | - |
Homo sapiens | 3-phosphooxypyruvate + NADH + H+ | - |
r | |
3-phosphooxypyruvate + NADH + H+ | - |
Homo sapiens | 3-phospho-D-glycerate + NAD+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
Phgdh | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens | |
NADH | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0203 | - |
pH 8.5, temperature not specified in the publication | Homo sapiens | 1-(4-chlorophenyl)-2-morpholino-2-thioxoethan-1-one | |
0.077 | - |
pH 8.5, temperature not specified in the publication | Homo sapiens | 1-(2,4-dichlorophenyl)-2-morpholino-2-thioxoethan-1-one | |
0.0851 | - |
pH 8.5, temperature not specified in the publication | Homo sapiens | 2-(4-methylpiperidin-1-yl)-1-phenyl-2-thioxoethan-1-one | |
0.0921 | - |
pH 8.5, temperature not specified in the publication | Homo sapiens | N-morpholinobenzenesulfonamide | |
0.106 | - |
pH 8.5, temperature not specified in the publication | Homo sapiens | morpholino(phenyl)methanethione | |
0.111 | - |
pH 8.5, temperature not specified in the publication | Homo sapiens | 2-morpholino-1-phenyl-2-thioxoethan-1-one |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme catalyzes the rate limiting step in serine biosynthesis pathway | Homo sapiens |