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Literature summary for 1.1.1.77 extracted from

  • Patel, E.H.; Paul, L.V.; Patrick, S.; Abratt, V.R.
    Rhamnose catabolism in Bacteroides thetaiotaomicron is controlled by the positive transcriptional regulator RhaR (2008), Res. Microbiol., 159, 678-684.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene rhaO, encoded in the rhaKIPAO gene cluster, expression analysis, transcriptional regulation of the rhaKIPAOR gene cluster, overview Bacteroides thetaiotaomicron

Protein Variants

Protein Variants Comment Organism
additional information a rhaO knockout mutant produces reduced levels of L-1,2-propanediol during growth in rhamnose, the mutant cannot utilise rhamnose as the sole carbon source but grows normally on glucose Bacteroides thetaiotaomicron

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-1,2-propanediol + NAD+ Bacteroides thetaiotaomicron
-
L-lactaldehyde + NADH + H+
-
?
L-1,2-propanediol + NAD+ Bacteroides thetaiotaomicron VPI-5482
-
L-lactaldehyde + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Bacteroides thetaiotaomicron
-
gene rhaO
-
Bacteroides thetaiotaomicron VPI-5482
-
gene rhaO
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-1,2-propanediol + NAD+
-
Bacteroides thetaiotaomicron L-lactaldehyde + NADH + H+
-
?
L-1,2-propanediol + NAD+
-
Bacteroides thetaiotaomicron VPI-5482 L-lactaldehyde + NADH + H+
-
?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Bacteroides thetaiotaomicron