Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH | Mus musculus | type 8 17beta-HSD can downregulate 17beta-estradiol levels in a large variety of tissues | 17beta-estradiol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
adult C57BL6 mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | in the three zones of the cortex, not in the medulla | Mus musculus | - |
corpus luteum | - |
Mus musculus | - |
epithelial cell | - |
Mus musculus | - |
kidney | epithelial cells of proximal convoluted tubules | Mus musculus | - |
liver | all hepatocytes | Mus musculus | - |
lung | bronchial epithelial cells and walls of pulmonary arteries | Mus musculus | - |
mammary gland | ductal epithelial cells and stromal cells | Mus musculus | - |
additional information | tissue distribution, in situ hybridization, overview | Mus musculus | - |
ovarian follicle | - |
Mus musculus | - |
pituitary gland | in three lobes | Mus musculus | - |
prostate gland | epithelial cells of the acini and stromal cells | Mus musculus | - |
uterus | in epithelial, luminal and glandular, and in stromal cells | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH | type 8 17beta-HSD can downregulate 17beta-estradiol levels in a large variety of tissues | Mus musculus | 17beta-estradiol + NADP+ | - |
? | |
estrone + NADPH | type 8 17beta-HSD is substrate-specific | Mus musculus | 17beta-estradiol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
type 8 17beta-HSD | - |
Mus musculus |
type 8 17beta-hydroxysteroid dehydrogenase | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Mus musculus |