Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.62 extracted from

  • Pelletier, G.; Van, L.; Li, S.; Labrie, F.
    Localization of type 8 17beta-hydroxysteroid dehydrogenase mRNA in mouse tissues as studied by in situ hybridization (2005), J. Histochem. Cytochem., 53, 1257-1271.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
estrone + NADPH Mus musculus type 8 17beta-HSD can downregulate 17beta-estradiol levels in a large variety of tissues 17beta-estradiol + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
adult C57BL6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland in the three zones of the cortex, not in the medulla Mus musculus
-
corpus luteum
-
Mus musculus
-
epithelial cell
-
Mus musculus
-
kidney epithelial cells of proximal convoluted tubules Mus musculus
-
liver all hepatocytes Mus musculus
-
lung bronchial epithelial cells and walls of pulmonary arteries Mus musculus
-
mammary gland ductal epithelial cells and stromal cells Mus musculus
-
additional information tissue distribution, in situ hybridization, overview Mus musculus
-
ovarian follicle
-
Mus musculus
-
pituitary gland in three lobes Mus musculus
-
prostate gland epithelial cells of the acini and stromal cells Mus musculus
-
uterus in epithelial, luminal and glandular, and in stromal cells Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estrone + NADPH type 8 17beta-HSD can downregulate 17beta-estradiol levels in a large variety of tissues Mus musculus 17beta-estradiol + NADP+
-
?
estrone + NADPH type 8 17beta-HSD is substrate-specific Mus musculus 17beta-estradiol + NADP+
-
?

Synonyms

Synonyms Comment Organism
type 8 17beta-HSD
-
Mus musculus
type 8 17beta-hydroxysteroid dehydrogenase
-
Mus musculus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Mus musculus