Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.62 extracted from

  • Husen, B.; Adamski, J.; Bruns, A.; Deluca, D.; Fuhrmann, K.; Moller, G.; Schwabe, I.; Einspanier, A.
    Characterization of 17beta-hydroxysteroid dehydrogenase type 7 in reproductive tissues of the marmoset monkey (2003), Biol. Reprod., 68, 2092-2099.
    View publication on PubMed
Search for more literature for 1.1.1.62

Cloned(Commentary)

Cloned (Comment) Organism
-
 Callithrix jacchus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
estrone + NADPH + H+ Callithrix jacchus final step in the synthesis of active estrogens, important in the maintenance of pregnancy estradiol-17beta + NADP+
-
 ?
estrone + NADPH + H+ Callithrix jacchus final step in the synthesis of active estrogens, important in the maintenance of pregnancy estradiol-17beta + NADP+
-
 r

Organism

Organism UniProt Comment Textmining
Callithrix jacchus Q9GME2 marmoset monkey, isoform 1, 17beta-HSD1
-
Callithrix jacchus Q9N0M8 marmoset monkey, isoform 7, 17beta-HSD7
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Callithrix jacchus
-
colon
-
 Callithrix jacchus
-
corpus luteum detectable throughout the luteal phase of the ovarian cycle and during pregnancy Callithrix jacchus
-
jejunum
-
 Callithrix jacchus
-
kidney
-
 Callithrix jacchus
-
liver high activity Callithrix jacchus
-
additional information not detectable in brain, colon, jejunum, pancreas, kidney, liver, adrenal, prostate, testis, uterus, lung, and spleen Callithrix jacchus
-
additional information not detectable in brain, lung and spleen Callithrix jacchus
-
pancreas
-
 Callithrix jacchus
-
placenta
-
 Callithrix jacchus
-
prostate gland
-
 Callithrix jacchus
-
testis
-
 Callithrix jacchus
-
uterus
-
 Callithrix jacchus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estrone + NADPH + H+
-
 Callithrix jacchus estradiol-17beta + NADP+
-
 ?
estrone + NADPH + H+ final step in the synthesis of active estrogens, important in the maintenance of pregnancy Callithrix jacchus estradiol-17beta + NADP+
-
 ?
estrone + NADPH + H+ final step in the synthesis of active estrogens, important in the maintenance of pregnancy Callithrix jacchus estradiol-17beta + NADP+
-
 r
estrone + NADPH + H+ reductive activity is 1.5-3fold higher than oxidative activity Callithrix jacchus estradiol-17beta + NADP+
-
 r

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Callithrix jacchus