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Literature summary for 1.1.1.58 extracted from

  • Hickman, J.; Ashwell, G.
    Uronic acid metabolism in bacteria. II Purification and properties of D-altronic acid and D-mannonic acid dehydrogenase in Escherichia coli (1960), J. Biol. Chem., 235, 1566-1570.
    View publication on PubMed
Search for more literature for 1.1.1.58

Inhibitors

Inhibitors Comment Organism Structure
p-chloromercuribenzoate slight inhibition, no inhibition below 10 mM Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 D-tagaturonate
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-altronate + NAD+ Escherichia coli
-
 D-tagaturonate + NADH
-
 r

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 ATCC 9637
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
68
-
 crude extract Escherichia coli
2730
-
 purified enzyme Escherichia coli

Storage Stability

Storage Stability Organism
3°C or frozen at -10°C, 1 month Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-altronate + NAD+
-
 Escherichia coli D-tagaturonate + NADH
-
 r

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Escherichia coli
NADH
-
 Escherichia coli