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Literature summary for 1.1.1.57 extracted from
- D-Mannonate: NAD-oxidoreductase from Escherichia coli K12. Kinetic studies of the enzymatic mechanism (1972), Eur. J. Biochem., 30, 220-233.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ATP | non-competitive | Escherichia coli |  |
| D-altronate | - |
Escherichia coli | |
| tagaturonate | competitive, inhibitory on forward reaction | Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-mannonate + NAD+ | Escherichia coli | - |
D-fructuronate + NADH | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
K 12 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-mannonate + NAD+ | - |
Escherichia coli | D-fructuronate + NADH | - |
r | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.3 | - |
for NADH oxidation | Escherichia coli |
| 8.4 | - |
for NAD reduction | Escherichia coli |
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Release 2023.1 (January 2023)
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