Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
17alpha-hydroxyprogesterone + NADPH + H+ | Rattus norvegicus | - |
17alpha,20beta-dihydroxy-4-pregnene-3-one + NADP+ | - |
? | |
progesterone + NADPH | Rattus norvegicus | - |
20beta-hydroxy-pregn-4-ene-3-one + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Fischer-344, especially male rats | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ | exhibits in male rat liver microsomes also a carbonyl reductase-like activity with acetohexamide as substrate | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17alpha-hydroxyprogesterone + NADPH + H+ | - |
Rattus norvegicus | 17alpha,20beta-dihydroxy-pregn-4-ene-3-one + NADP+ | - |
? | |
17alpha-hydroxyprogesterone + NADPH + H+ | - |
Rattus norvegicus | 17alpha,20beta-dihydroxy-4-pregnene-3-one + NADP+ | - |
? | |
4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide + NADPH | male-specific and androgen-dependent activity, competitive to progesterone, cortisone, cortisol and 17alpha-hydroxyprogestrone consumption | Rattus norvegicus | hydroxyhexamide + NADP+ | - |
? | |
cortisone + NAD(P)H | - |
Rattus norvegicus | 17alpha,20beta,21-trihydroxy-pregn-4-ene-3,11-dione + NAD(P)+ | - |
? | |
progesterone + NAD(P)H | - |
Rattus norvegicus | 20beta-hydroxy-pregn-4-ene-3-one + NAD(P)+ | - |
? | |
progesterone + NADPH | - |
Rattus norvegicus | 20beta-hydroxy-pregn-4-ene-3-one + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |