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Literature summary for 1.1.1.51 extracted from

  • Durocher, F.; Sanchez, R.; Ricketts, M.L.; Labrie, Y.; Laudet, V.; Simard, J.
    Characterization of the guinea pig 3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4-isomerase expressed in the adrenal gland and gonads (2005), J. Steroid Biochem. Mol. Biol., 97, 289-298.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, phylogenetic analysis Cavia porcellus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
41475
-
x * 41475, amino acid sequence calculation Cavia porcellus

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
Cavia porcellus
-
gonad
-
Cavia porcellus
-
ovary
-
Cavia porcellus
-
testis
-
Cavia porcellus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dehydroepiandrosterone + NADPH + H+ reduction at C17 Cavia porcellus 5-androstene-3beta,17beta-diol + NADP+
-
?
pregnenolone + NADPH
-
Cavia porcellus progesterone + NADP+
-
?

Subunits

Subunits Comment Organism
? x * 41475, amino acid sequence calculation Cavia porcellus

Synonyms

Synonyms Comment Organism
17beta-HSD type II
-
Cavia porcellus
3beta-HSD
-
Cavia porcellus
3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4-isomerase
-
Cavia porcellus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Cavia porcellus