Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ellagic acid | mixed type inhibitor of glucose 6-phosphate activity | Plasmodium falciparum | |
additional information | presence of H2O2 only slightly alters enzyme activity or expression | Plasmodium falciparum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Plasmodium falciparum | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | Q8IKU0 | bifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 109000, calculated from sequence, x * 100000, SDS-PAGE | Plasmodium falciparum |
Synonyms | Comment | Organism |
---|---|---|
PF14_0511 | - |
Plasmodium falciparum |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000076 | - |
pH 7.5, 25°C | Plasmodium falciparum | ellagic acid |
Organism | Comment | Expression |
---|---|---|
Plasmodium falciparum | no significant upregulation of expression in presence of artemisinin, chloroquine or methylene blue | additional information |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is essential for the growth of blood stage parasites | Plasmodium falciparum |